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العنوان
Evaluation of the effect of Phacoemulsification surgery on retinal and choroidal microvasculature in diabetic patients using optical coherence tomography angiography /
المؤلف
Abdel Malek, Sara Nazem Naguib.
هيئة الاعداد
باحث / سارة ناظم نـجيب عبد الملك
مشرف / علاء فتحى محمود
مشرف / تامر فهمي عليوة
مشرف / منى كمال عبد اللطيف
تاريخ النشر
2023.
عدد الصفحات
120 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
طب العيون
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - قسم طب وجراحة العيون
الفهرس
Only 14 pages are availabe for public view

from 120

from 120

Abstract

D
iabetic retinopathy is one of the leading causes of blindness worldwide. Diabetic macular ischemic that develops in advanced diabetic retinopathy cases is considered one if the irreversible caused of loss of vision in diabetic eyes. Optical Coherence Tomography angiography (OCTA) is a new, noninvasive and diagnostic tool which serves to assess the perfusion of different areas of the retina as well as the optic disc. It is used to diagnose and follow up eyes with diabetic maculopathy.
Phacoemulsification surgery is the standard procedure for cataract extraction and studies are ongoing to evaluate the effect of this intervention on the retinal vascularity and perfusion. Our study comprised 50 cataractous eyes undergoing phacoemulsification, 25 eyes of diabetic patients and 25 eyes of controls. We evaluated the effect of the surgery on retinal perfusion using OCTA. Our study revealed that diabetic eyes have lower mean preoperative parafoveal choriocapillaris vessel density. We also found that the perifoveal area in the diabetic group showed significantly lower mean choriocapillaris vessel density than the controls till the 3rd month postoperatively. However, all the studied parameters were not different by the 6th postoperative month.
Our preliminary finding is that phacoemulsification surgery may lead to the transient reduction of choroidal blood flow and hypoxia in diabetic eyes.
CONCLUSION
P
hacoemulsification surgery may lead to the transient and mild reduction of choroidal blood flow in diabetic eyes rather than retinal blood flow. Most of choroidal and retinal vascular change happened in the perifoveal area within 1 week to 1 month postoperatively and may extend to 3months.