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العنوان
Evaluation of Serum Interleukin (IL)-17A and IL-22 Levels in Pediatric Patients with Autism /
المؤلف
Shaker,Youstina Sabry
هيئة الاعداد
باحث / يوستينا صبري شاكر
مشرف / جيهان احمد مصطفى
مشرف / ريهام محمد الحسينى
مشرف / دينا ابراهيم درويش سلام
مشرف / سارة ابراهيم عبد الفتاح
تاريخ النشر
2023
عدد الصفحات
107.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 107

from 107

Abstract

Results: we had 48 subjects, where we had 24 autistic child and similar age and gender matched controls, with median (IQR) age of 5.25(5 – 8) and 6(5 – 9) years respectively, where we had a male predominance (68.75%). The median serum level of IL-17A and IL-22 were significantly higher in autism patients than controls, where serum level of IL-17 was 262.5 (235 – 320) pg/mL in autistic patients versus 35 (25 – 47.5) pg/mL in controls, meanwhile IL-22 in autistic patient was 800 (680 – 975) pg/mL versus 50 (45 – 65) pg/mL in controls (p=<0.001).
Conclusion: Our findings suggest that elevated levels of IL-17A and IL-22 may be associated with autism. Further research is needed for better understanding the role of these cytokines in autism and their potential implications for diagnosis and treatment.