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العنوان
Comparison between manual and automated CT liver volumetry in assessment of the liver volume in living donor liver transplantation /
المؤلف
Mohamed, Eslam Mahmoud Taha.
هيئة الاعداد
باحث / إسلام محمود طه محمد
مشرف / أمنية أحمد كمال
مشرف / إيناس أحمد عزب
مشرف / أحمد عبدالسميع محمود
مشرف / عماد حامد عبد الدايم
تاريخ النشر
2019.
عدد الصفحات
129 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

from 129

from 129

Abstract

Living-donor liver transplantation procedure has emerged as a valuable alternative as it allows healthy adults to donate a part of their own liver to a compatible recipient.
The success of living donor liver transplantation lies in the unique anatomy and physiology of liver which allows for partial liver graft procurement from a living donor. In healthy donors, remnant liver volume of 30 % for the liver is considered to be a safe threshold for transplantation to proceed, provided that liver is normal or there is minimal steatosis.
Multiple imaging modalities have been exploited to measure the volume of future liver remnant, including computed tomography (CT), magnetic resonance imaging (MRI), as well as ultrasound.
Among these, most authors consider computed tomography manual volumetry to be the current gold standard. Generally, radiologists have to manually delineate the liver region slice by slice, which is tedious and time-consuming due to the large amount of data.
Automated liver volumetric method has been shown to improve accuracy while reducing processing times.
In our study, automated volumetry achieved excellent agreement with manual volumetry without statistical significance. We also found that the automated method was 5.25 times faster than the manual method.
In our study, eight potential donors underwent right hepatectomy excluding MHV and we compared data obtained from preoperative volumetric measurement and intraoperative actual graft weight. Our results revealed that both manual and automated volumetric measurements showed significant positive correlations between their estimated volumes and the actual graft weights.
In conclusion, automated CT liver volumetry performed with the Myrian® XP-Liver software significantly reduced the time required for volumetry of the liver, accurately predicted the preoperative liver volume and provided acceptable measurements comparable to the gold standard manual volumetry.
By using our study data obtained from preoperative volumetric measurement and intraoperative weight/volume of the grafts, we concluded that manual and automated CT liver volumetry provide acceptable volumetric measurements that can be considered sufficiently accurate for determination of weight/volume of liver graft for surgery.