الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
The acute toxicity of the tested organophosphorus compounds (Dursban and Curacron) and carbamates (Lannate and Famid) were determined against the housefly (topically), mosquito larvae (water immersion), end white mice (orally). The method of Litchfield andWilcoxon (1949) was applied for analysis of the data. The ins6ccicidal effects of the tested organophosph atea against t he housefly showed that C uracron WES the most toxic compound followcld by Durs ban. In respect to carbamates, lannate showed highclr toxici ty than Famid. The toxicity of the tested compounde showed enotl.:3r pattern against the mosquito larvBe. However, mosquito larvae were extremely scnsi ti VG to the orga nophos phorus oompound s. In the same time Dursben was more toxic to m08qui to lervE e thEn Curacron. The carbem8tes studied were fairly toxic, end L8nnate was more toxic than Famid. The ffi8mm8lian toxicity of the studied organophos p~te8 followed a pattern different from their effectiveness ageins t the hous 6 fly. The order of the organophosphatee studied based on ora 1 LD50 value for each compound was aa follows: Dura ban, than, Cura crOn. While car bame te a .toxici ty followed El pGttqrn sim.ilar to .thCit on the housefly o.nd it was: Lcnnate followed by Famid. From the relative toxicity data, we can say that the tested organophosphatcis veried considerably in their toxicity to insects and mammals. ’£he compound which was highly toxic to thG insdcts WES not necessarily the most toxic to mammals end vic e v er sa. While carbemates showed a relation bcitwaen tho ins~ticidel activity and memmalian toxicity. In vitro anticholingstdr5scl measurements showed that the order of potan...:y of thcl organophosphatos used in inhib . iting the fly head ChE wes: Curacron followdd by Dursban, and this ordclr is in agre0mdnt wi th their acutd toxici ty. While the orddr 01 cerbamatd 8 was: Lannate, then, Famid_.’ Also, this orddr is in agreemont with the acute. toxicity of carbematsa to the hous,Hly. Nhen~he total homogunete of the mosquito larvae used, it wes found that ChB anzym0 was insensitivG to Curacron, while Dureban show-::d moderate inhibi tory action. In rdspect to carbamate8 , Lennete showad higher inhibitory action than Famid.. The order of orgenophosphates against mice brain ChE as indic B ted by in vi tro 150 was: Curacron followed by Dura ban, and the ord er of cer bama te 8 was: Famid, then, LBnnate. In order to correlatG between the relative toxicity a~ antich0lindstere8G activity of the tested insecticides, the in vitro ISO’S compared with the lethal action of thes6 compounds. It is obvious from the data that the relative toxicities of both organophosphatea and carbamates Egainst the housdfly iollowed their inhibitory action. Also, there was a direct relation betw60n toxicity and snticholinesteras6 activity in the case of mosquito larvae. While the me:.:unEli~n toxicity failed to correlate with the inhibitory action of these compounds. ^leng