الفهرس | Only 14 pages are availabe for public view |
Abstract The environmental medium of the sperm is very important for its survival and activity. A change in the biophysical and biochemical set-up of the seminal plasma due to variation in the level of its constituents can affect the normal life of the gamete. A number of studies have been taken place estimating different constituents present in the seminal plasma / ca) and was compared to that of infertile subjects. Exhaustive efforts have been made in the search for enzymatic parameters useful as markers of specific events in testicular function. The present study was carried out to investigate the possibility of using a seminal plasma enzyme profile as a biological marker of testicular function. The activity of seminal plasma aspartate aminotransferase (AST), Alanine aminotransferase (ALT), B-glucuronidase (B-Glase), Gamma-glutamyl-transpeptidase (GGTP) and Acid phosphatase (AP) are measured in the fresh semen samples of 40 men, ten normospermic subjects, ten oligospermic, ten severe oligospermic and ten azospermic patients. The oligospermic, severe oligospermic and azospermic seminal plasma enzyme profile have a significant elevation in the activities of (AP), (B-Glase) and (GGTP) compared with the level of these enzymes in normo¬spermic cases. whereas, a significant decrease in (AST) and (ALT) activities were observed in those patients compared to the level of these two enzymes in normospermic cases. A significant positive correlations exist between the activities of (AST |