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Abstract Perimenopusal bleeding is commonly encountered in gynecological practice. It accounts for almost 25% of gynecological operations and 20% of office visits. Many causes of perimenopusal bleeding as endometrial hyperplasia, uterine fibroids, endometrial polyps and malignancy. So it requires accurate diagnosis of the cause especially endometrial hyperplasia for the possibility of malignancy transformation and many methods used for diagnosis. These methods are either non-invasive or invas ye technigves. The Bon-IivasiveIJJetho1i4 jjJ’c’ 1’ helpful in diagnosis, as pelvic ultrasonography, transvaginal ultrasonography, hysterosalpingogram, sonohysterography, color Doppler andMRl. Invasive techniques are also very helpful in diagnosis of endometrial hyperplasia, as hysteroscopy and endometrial sampling. Endometrial biopsy and tissue examination is considered an important diagnostic tool for the evaluation of endometrial hyperplasia. The Iocumented safety and accuracy of plastic endometrial sampling devices ave made them popular for office use. However, some complications were reported with the use of D&C biopsy, range from slight lower abdominal pain after D&C to perforation of the uterus, infection, bleeding, uterine synechiae, amenorrhea, infertility and irmalities of placental attachment in later pregnancies are possible after . |