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العنوان
Evaluation of levels of cholinesterase enzyme in albino rat in relation to various toxic doses of the organophosphorus inseticide ”cyanophos” \
المؤلف
El-Seidy, Amira Mohamed Mahmoud.
هيئة الاعداد
باحث / Amira Mohamed Mahmoud El-Seidy
مشرف / Samy Moustafa Badawy,
مناقش / Sahar Mohamed Kamel
مناقش / Tarek Fouad Abd EL-Hakim
الموضوع
Forensic Medicine.
تاريخ النشر
1999.
عدد الصفحات
188 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/1999
مكان الإجازة
جامعة المنوفية - كلية الطب - Forensic Medicine
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study was carried out primarily to evaluate the ixicological effects of the organophosphorus insecticide ”cyanophos fter administration of variable toxic doses given once and after giving)w dose repeatedly.
he study included the following:
Effect of variable oral doses i.e. LDso Va LDao and ^lo LDso given nee.
Effect of repeated low dose ^/m LDso given for 3 consecutive days).
he evaluation included both clinical manifestations and level of hohnesterase enzyme inhibition in serum and organs (liver, heart and train).
Effect of time on recovery after giving repeated low dose.
[he study was carried out on 70 male albino rats, which were divided into i groups: 1,11, III, IV and V The first group (group I) was given normal saline (the vehicle) and I served as a control group for comparison with other groups.
| Groups II, III and IV were given single oral doses equivalent to LDso Y2LD50 and l lo LDso respectively.
Animals of group V were divided into 3 equal subgroups (a, b and c)and were exposed to repeated low dose of cyanophosicLDso for 3 consecutive days.