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Abstract
o compare the efficacy of the addition of Tamsulosin or Terazosin to the standard expulsive pharmacologic therapy for the treatment of distal ureteral stones.
Patients and methods: A series of patients referred to our department for the management of symptomatic distal ureteral calculi were randomly divided into group 1 (N=15) who received standard medical treatment, group 2 (N=15) who received the same standard medical treatment plus Terazosin (5mg) and group 3 (N=15) who received the same standard medical treatment plus Tamsulosin (0.4mg) for maximum 1 month. There were no differences between the groups with respect to age, sex, or stone size. The primary end point was the expulsion of the stone. Expulsion time, need for analgesics, need for hospitalization, and drug side effects were the secondary endpoints.
Results: the expulsion rate is significantly higher in group3 and group 2 (67%, 80% respectively) than in group 1(53%). Lower analgesic use was found in groups 2 and group 3 as well as significantly fewer hospitalizations for recurrent renal colic.