الفهرس 
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Abstract
Abnormal bleeding tendency in patients with advanced chronic renal failure has been observed for many years as a frequent well known and important complication.
A variable combination of prolonged bleeding time, abnormal platelet adhesiveness, decreased platelet aggre¬gation to AD P and thrombin, and reduced PP3 availability characterize the haemostatic defect of chronic renal failure.
Platelets are the chief source of PL for the intrinsic blood coagulation process, also platelet phospholipids fulfill the requirement of lipid like material for the full activity of tissue factor which activates the extrinsic blood coagulation mechanism.
Platelet phospholipids undergo significant alteration during aggregation induced by thrombin or other agents.
Iriany teats have been used in coagulation to show the behaviour of isolated PL fractions in different clotting system: PB fraction is effective in shortening the recaloified clotting time. PS fraction is active in TGT and also effective in shortening the recalcified clotting time. PC fraction is equally active as PE for fulfilling the activity of tissue