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Abstract
Autistic spectrum disorder is a complex developmental disorder with social and communication dysfunction at its core. Autistic spectrum disorder are a wide spectrum of conditions have a common triad of impairments. Deficits include those in social communication, social interaction and social imagination. Autism is a developmental disorder of the human brain that first gives signs during infancy or childhood and follows a steady course without remission or relapse. Impairments result from maturation-related changes in various systems of the brain.
This work was designed to evaluate patients with autistic disorders through detailed history and rating their severity using CARS. The brain dysfunction in autistic patients (AD) was evaluated through assessment of the major metabolites ratios using MRS in the left side of limbic system (hippocampus-amygdala) and cerebellum.