الفهرس 
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Abstract
The current study was conducted to evaluate clinically, radiographically and biochemically the application of a local dose of alendronate sodium gel in management of bony defects in periodontal pocket in chronic periodontitis patients A total number of forty systemically healthy. Chronic periodontitis male patients were recruited for the clinical study. Prior to treatment, they were placed on a comprehensive oral hygiene program. Full-mouth scaling and root planning were performed. This phase lasted till the O’Leary plaque index( ) approached a value of about 10%.
Forty male patients were randomly assigned to one of the following groups:
Group I: Comprised 20 patients that were managed by scaling, root plassning and adjunctive use of 20 mg of alendronate sodium gel in periodontal pockets.
Group II: Comprised 20 patients that were treated with scaling and root planning alone.
The following clinical parameters were recorded at baseline, three, six and nine months postoperatively. Gingival index(201), probing pocket depth(202) and clinical attachment level.(202)
Furthermore, standardized periapical radiographs were taken at base line, and repeated at three, six and nine months after surgery. Linear and densitometric analysis of radiographs were measured using computer assessed program image(203) in order to record alveolar bone height and radiographic optical density at these time points.
Statistical analysis of results revealed a significant reduction of probing pocket depth in the two groups at three, six and nine months when compared to preoperative values.