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Abstract Osteoarthritis is defined as a complex of interactive degenerative and repair process in cartilage, bone and synovium with secondary components of inflammation. It is a slowly progressive disease, affecting principally hands and large weight bearing joints. This disease was discovered in prehistoric fossils and Egyptian mummies. Osteoarthritis is classified into two main categories: I. Idiopathic A. Localized B. Generalized (GOA) II. Secondary to other causes. E.g. trauma, congenital, etc. |