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Abstract This study was conducted to evaluate laboratory and clinically the effect of treating soft liners, with permaseal sealant on surface integrity (Surface Condition) and find out its wettability and hygienicity over a 6 months period. Twenty-four completely edentulous patients were Selected for microbiological evaluation, each patient received upper and lower heat-cured acrylic complete dentures, the upper and lower dentures were constructed in the usual manner, but the upper denture fitting surface was provided with a layer of aluminum foils during washing up stage, after curing, the patients were divided into four subgroups. Group I (a): Silicone soft liner left uncoated Group I (b): Silicone soft liner treated with permaseal sealant. Group II (a): Acrylic Coe-soft left uncoated. Group II (b): Acrylic Coe-soft treated with permaseal. For surface texture evaluation, eighth square samples were selected, two from each group after 1, 3 and 6 months post-insertion. Changes in the surface texture of the soft liner was analyzed with the scanning electron microscope |