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Abstract The variations of stiffness and mass are considerable factors that affect the seismic response of reinforced concrete structures. Seismic codes provisions restrict the use of equivalent static force method for estimating earthquake loads to regular buildings. These codes provide limited values for variations in stiffness and mass beyond which dynamic analysis is required. The variation of infill panels is another factor that affects significantly the seismic response of reinforced concrete structures. This factor is not taken into consideration in equivalent static method. The effect of variation of stiffness, mass and infill panels on ...- frame-type reinforced concrete buildings will be investigated using a non-linear dynamic analysis program. The obtained results will be compared with results from the equivalent static linear method recommended by different codes. A parametric study of this <, research consists of nine groups of infill two-dimensional frames with variable heights for each group. Each group consists of three frames will be studied and analyzed under the effect of different earthquake records. The variable of the first three groups will be the irregularities of stiffness by changing the position of the columns of the frame at different stories. The variable of the second three groups will be the irregularities of mass by considering an increase in mass at specific stories due to variations in function/use. The variable of the third three groups will be the locations of infill panels. from the results obtained from the parametric study of the variation of mass, stiffness and infill panels some conclusions and recommendations will be obtained. |