الفهرس Only 14 pages are availabe for public view
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Abstract
This study was carried out to evaluate the prophylactic and therapeutic efficacy of vitamin E and zinc, from pathological and biochemical points of view, against chronic copper toxicosis in albino rats. Therefore, one hundred and fifty six male albino rats of nearly similar weight (approximately 120 g) were used. Two experiment were conducted, the first experiment aimed to study the probable protective effect of zinc sulfate and vitamin E against copper toxicosis. Four groups of rats 24 each were fed for 8 weeks as follows: Group (GP) 1: the basal diet (control), GP2: the basal diet containing copper sulfate (4000 ppm), GP3: the basal diet containing copper sulfate (4000 ppm) and vitamin E (270 ppm), and GP4: the basal diet containing copper sulfate (4000 ppm) and zinc sulfate (227 ppm) in drinking water. The second experiment was carried out to evaluate the probable therapeutic effect of zinc sulfate and vitamin E against copper toxicosis