الفهرس 
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Abstract
This study included 154 burned patients who were admitted to the N.B.U and the E.U at the Main Hospital of’Alexandria University. It was ’carried over a 6 months, period, begining ,: from March 1985 to August 1985. Samples were taken from these patients on admission and twice weekly from one or more sites if needed till their discharge from the units or their death. These samples were cultured on suitable media and the ~solated colonies were identified and tested , for their susceptibility to antibiotics. The data collected in this study are summerized as follows: -1- The bacteria isolated in the studied burn units fell into two groups. The pathogenic group included Ps. aeruginosa, K. aerogenes, Proteus species (...P. mirabilis, P. morgani, P. retgerri and P. vulgaris ), E. coli, Serr. marcescens and Staph. aureus. The non pathogenic group ( Saprophytic) included the micrococci , N. ca tarrhalis - . and Gram-positive bacilli ( anthracoids and diphtheroids ) -2- Negative specimens ( Saprophytic + Sterile) represented 12.86 of the total specimens taken from patients in the ” N.B.U: while they were 29.56 of the specimens of the E.U. -}- The isolation of pathogenic Gram-negative bacilli was greater from deep burns than that from the superficial burns and the reverse occured with th~ negative specimens. -4- The occurQnce of Ps. aeru~inosa and other Gram-negative bacilli was higher in burn wounds on the lower half of the body than those on the upper half, while Staph. aureus and saprophytic bacteria occured in higher frequency in burn wounds on the upper half of the body. ¬ -5- The occurance of almost all pathQGenic Gram-negative bacilli was higher in burn wounds of patients in the age group over 60 years. . -6- The occur~nce of Gram-negative bacilli was low on , admission but gradually increased with time till it reached its peak by the end of the third week of inj ury, then their frequency declined again .to be replaced by negoti ve $pecimens. -7- The burn wounds with large sur~ace areas ( 30 - 50 ) were more liable to be infected with pathogenic bacteria ” such as Ps. .aeruginosa, K. aerogenes and Proteus species than the smaller burn wounds which were more liable to be colonized by saprophytic bacteria Qr remained sterile for longer time. -8- Graft failure ( reinfection of the burn wound after escharectomy and grafting) was more in the E.V. than in the N.B.D. -9- The administration of proper systemic antibiotics in treatment of burn infection in the N.E.U was more efficient than their administration blindly in the E.U. -10- The isolated ~. aerut>i:nosa strains were sensitive only to 8 broad spectrum antibiotics ( Rifampicin, Amikacin, Garamycin, Kanamycin, Tobramycin, Polymyxin B, Ampiclox, and Cluforan)out of 19 antibiotics tested. -11- Amikacin- a member of aminoglycoside group of antibiotics was active against almost al~ isolated pathogenic bacteria, its efficiency ranged from 86.21 Staph. aureus to 100 . . for Serr. marcescens. -12- During the performance of this study, 6 patients died within the first J days of their admission ( from burn shock) and 16 died after one week or more~out of them 81.25 harboured Ps. aeruginosa in their burn wounds. -13- Out of the 12 pBrformed blood cultures from patients showing signs.of septicaemia, 4 gave positive results -14- As this study was performed just after general disinfection of the N.B.U, during the first 2 months ( March and April) almost all specimens from the N.B.U were negative, but positive results started to appear in the third month ( May) and increased gradually till the end of the fifth month ( July), when the unit was disinfected again~the occurance of positive results fell in August to a low percentage.