الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
The role of trace elements in human health is a matter of growing concern to biochemical scientists since there an evidence of a relationship between the concentration is of trace elements in natural environment and their concentration ID s~ & subsequently the occurance of various diseases Because of the different nature of the sourCes of dti nking water in South Sinai than in other areas of Egypt, it it was expected that the concentration of trace elements in water sour ces to be diff erent from other areas of Egypt. The environmental variations of some trace elements was reflected In their concentration in the sera of j;X).pul ation and also in fluenced the nature of the health problems. The aim of this stldy is to determine the possible ass Jciation between the concentration of trace elements in the different water sources in South Sinai and their correspond ing concentration in the sera of adult male subj ects In addition, the association between the prevalent health probl ems and the serum concentration of some trace elements will be evaluated. The study was carried out on 100 adult healthy males aged 25-45 years, selected at random from lias’ Budran in South S,inai . A control group of 50 adult healthy mal e s matched for the same age, sex and socio-economic standard was taken from Al exandr ia city. Both subjects and controls were in tervi ewed for their personal data & environmental variables using a preschedu led observation sheet, then subjected to complete; clinical examination with special emphesis on heart complaints Complete blood picture, sedementation rate, urine analysis and parasitic stools examination were done to the subjects and controls according to the standard methods .A\lso , samples from their blood were examined for the 1 evels of the selected trace elements (i.~a Iron, Zinc, copper & cad miu:n) u sir.g the atomic absorption spectrophotometer. Rega rding the environmental samples, 12 samples were collected at random from the drinking well water of Ras Budran and another 12 sam~les collected also at random from Alexandria potable surface water as a control, both samples were test ed for its levels of the selected trace elements using the atomic absorption spectrophotometer, together with its physical & chemical properties. The ~esults of the present work revealed that, the subjects from Ras BuJran which is a desert comnunity dep ending on well water for drinking were significantly diffe rent from the controls living in Alexandria districts depe njing on potable surface water as drinking water This difference included, serum ziJ1c levels, R. 3. Cs. count & blood pressure where the subjects from Ras a.d.ran had a lower mean values of these three variables compared vd t h Alexandria controls. Also, the results of the study revealed that there is a significant difference between the Alexandria potable surface water and the Ras Budran well water concerning its nnc levels & degree of hardness, where the water samples from Ras &1uran had a IIUchlower levels’ of zinc than Alexa . nndria water samples, meanwhile, this water from Ras ~~jran had a higher degr ee of hardness than Al exandria potable surf ace water samples. Also, the study revealed that the correlation between ’the serUTI levels of the selected trace elements and the concentration of these elements in water is quite present, also the correlation between the health problems and the serun concentration of the selected trace elements. The stilly recomnended further investigation in the relation-ship between the man and his environments concern in’j the trace elements, where extension of the resem:;che must cov~the industrial & rural comnunities, together with the stilly of other factors that marke-dly aff ect the trace eleme nts level s in human body rather than drinking water (e.g. food & air) . Also, the study recommended further investigations on the role played by the trace elements in production of cardi:”’” vascular disease and its relation to water hardness.