الفهرس 
ORGANIC PHOSPHORUS COMPOUNDSOnly 14 pages are availabe for public view
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Abstract
Malathion is one of the most widely used organophosphorus insecticides because of its potent insecticidal activity and relatively low mammalian toxicity. Manifestations of malathion toxicity are due to inhibition of the enzyme acetylcholinesterase. This results in accumulation of acetylcholine with subsequent muscarinic and nicotinic effects. In addition, malathion is recently accused of producing hepatic damage through an oxidative stress mechanism. Ginger is one of the most widely used spices and is a common condiment for a variety of foods and beverages. Ginger’s phenolic conslilucnis have been found to possess many interesting pharmacological activities, such as anti-inflammatory, antioxidant, and antihepatotoxic effects. Hence, the present study was conducted to investigate the toxic eflects of malathion on the liver with the possibility of inducing oxidative stress. Additionally, the potential protective effect of ginger on malathion-induced liver damage was investigated, in comparison with vitamin C.