الفهرس | Only 14 pages are availabe for public view |
Abstract Several pathophysiological mechanisms have been proposed for the development of polycystic ovary syndrome. Numerous reports confirm the role of vascular endothelial growth factor as an important mediator of the syndrome. It induces strong angiogenic response, accompanied by extensive cyst formation in the ovary. The primary cause of polycystic ovary syndrome is still unknown so treatment is directed at the symptoms of the disorder. Few treatment approaches improve all aspects of the syndrome but the patient’s desire for fertility must be respected. Despite of the high success rate of clomiphene citrate in most anovulatory women, treatment has low success rates in inducing ovulation in women with polycystic ovary syndrome. We are looking forward to test other angiogenic factors which might be helpful as predictors for the effect of NAC as an adjuvant to CC |