الفهرس 
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Abstract
The early hours of acute myocardial infarction is a critical period as more than 60 percent of the deaths associated with acute myocardial infarction occur within the first few hours of the event. Early treatment with thrombolytic therapy restore myocardial blood flow (reperfusion) and reduce mortality. So, early diagnosis of myocardial infarction is very
important. The aim of our study is to evalute a new approach for early diagnosis of acute myocardial infarction by immunoturbidimetric myoglobin assay. Also, we compare this test with other important investigations which are used to diagnose acute myocardial infarction as: electrocardiographic changes and serum creatine kinase.
The present study included 24 patients suffering from acute chest pain suspicions of AMI and also five completely healthy persons as a control. All patients and control had been undergo: electrocardiographic monitoring, determination of serum creatine kinase level in blood and determination of myoglobin level in
blood by turbidimetric immunoassy.
from these 24 patients, 15 patients proved to have myocardial infarction as final diagnosis. 13 patients only admitted within six hours from the onset of pain. Nine patients only from those 13 proved to have myocardial infarction. The sensitivity of myoglobin in all patients with infarction was 86.6% and the specificity was 100%, while the sensitivity and specificity of CK was 60% and 100% respectively. Sensitivity and specificity of myoglobin in patients admitted in the first six hours from the onset of pain was 88.8% and 100% respectively. Sensitivity and specificity of E.C.G in all patients with infarction was 66.6% and 100% respectively.
We can conclude from this study that the serum myoglobin assay is a sensitive and specific test to diagnose acute myocardial infarction in the first few hours. The immunoturbidimetric assay is a rapid, reliable and sensitive method for quantitative measurement of myoglobin level. Also, we can conclude that the serum myoglobin assay can identify those patients without definite E.C.G changes.