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Abstract This study was conducted on 35 subjects divided into the following groups : - Group ( 1 ) : 20 patients ( non-uraemic, non-diabetic and non-hypertensive ) receiving radiographic C.M. - Group ( 2 ) : 15 normal persons as control receiving normal saline. Thorough history & clinical examination was performed to every subject with special stress on age, sex, clinical presentation, ....... The following investigations were performed : Urine for Microalbuminuria before & 24 hr after CM, and for alkaline phosphatase before & 5 hr, 24 hr and 5 days after CM. S.creatinine, blood urea, & fasting blood sugar with special stress on Microalbuminuria, urinary ALP & S.creatinine at known intervals before and after C.M. administration. The following were drawn from our work : Results : Significant increase of microalbuminuria 24hr after CM ( Means 326.1 ± 82.0 ). Significant increase of urinary ALP 5hr after CM ( 79.8 ± 19.5 ). Significant increase of S. creatinine after 48hr reaching a peak long after CM ( Means 2 weeks after CM 2.25 ± 1.35 ). Significant increase of microalbuminuria & enzymuria among diabetic patients ( 377.2 ± 99.5 for microalbuminuria & 79.4 ± 26.9 for enzymuria ). Conclusion : Therefore the detection of microalbuminuria & enzymuria is of benefecial value for early diagnosis of occult RCIN. |