Search In this Thesis
   Search In this Thesis  
العنوان
sister chromatid exchange in juvenile rheum atoid aethitis/
الناشر
abdallah gushy abdel haliem,
المؤلف
abdel_haliem,abdallah gushy
هيئة الاعداد
باحث / abdallah gushy abdel haliem
مشرف / shaheen dabour
مشرف / suzan farouk
مناقش / mohamed el_sayed
مناقش / ,kahlid abdou mohamed
الموضوع
faculty of medicine_pathology pathology
عدد الصفحات
122p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة بنها - كلية طب بشري - اطفال
الفهرس
Only 14 pages are availabe for public view

from 135

from 135

Abstract

Summary
SUMMARY
Juvenile rheumatoid arthritis is the most common rheumatic
disorder of childhood. The knee is the most frequently affected
joint with the increasing viability and use of disease-medifyin~
antirheum atic drugs. Demonstration of SCE has become - important. ..
_ SCE are performed on patients with JRA for a variety of
reasons: to determine the subtypes of JRA, detect the extend
of the disease, and to evaluate progression of the disease; and
to judge the effica’10f drug treatment. The study included 20
patients with JRA who attended the pediatric rheumatology
clinical, Benha teachign hospital for regular follow up. They
all presented below the age of 16 years; with a mean age 9.95
+ 3.15years. patients were classified into 3 subgroups.
according to American criteria of reheumatology for J.R.A j... .
group Ia included 6 patients with oligoarticular J.R.A. group
Ib 6 patients with polyarticular J.R.A, Group Ic 8 patients
with systemic J.R.A.
The study also include 10 control volunteers. All cases were
subjected to full clinical and rheumatologcialevaluations.
Routine laboratory .investigation including complete
haemogram with platelets count; ESR, CPR, ANA, RF and
SCE.
-103-
~ -- -- -----------
Summary
When looking to the frequency of different clinical
presentation in J .R.A. there was a Regarding laboratory data
strong statistical differences were detected between the two
groups of studying in platelet count, ESR, and positive CRP.
When concerning the SCE findings of J.R.A. patients and
control volunteers there were highly statistically significant in
systemic J.R.A. significant in polyarticular type and non
significant in oligoartricular J .R.A. there were a strong
position significant correlation were detected clinically and
by ESR, CRP and SCE p <0.05 which was significant and it
directly proportional in oligoaticular type but highly
significant p <0.001 and it was highly significant p <0.001
directly proportional.