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Abstract By the time patients have readied end-stage renal disease and need dialysis, a majority are experiencing debilitating fatigue and lack of energy. Few dialysis patients are gainfully employed and many are unable to care for themselves. The pervasive feeling of fatigue among ureinic patients, in conjunction with the growing proportion of elderly and very old patients on dialysis, makes it necessary for nephrologisls to focus their attention on which factors actually are responsible for their patients dysfunction in their everyday lives. The aim of this study is to measure the physical working capacity in end-stage renal disease patients undergoing maintenance hemodialysis.Correlation with the adequacy of dialysis, nutritional status and some other parameters will be performed in a trial to find which parameters have a significant effect. The study was conducted on: • 30 patients with end-stage renal disease under the treatment of maintenance I ID for at least one-year. • 20 normal subjects of comparable age and sex Patients suffering from diseases that would affect the physical working capacity in particular the cardiovascular system (e.g. isehemic heart disease) and the respiratory system (e.g. chronic obstructive pulmonary disease) were excluded. |