الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 198 |  |  |
| | | from | 198 | | |
Abstract
Bacterial infections are common complications in cirrhosis (about 40%) especially if cirrhosis with bleeding and these infections may a role in inactivation of coagulation system and interference with hemostasis and thus rebleeding, by simulation of nitric oxide decrease platelet function that causes deterioration of primary hemostasis and favour bleeding of oesophageal varices . Nitric oxide is highly biologic, immunologic and vascular mediator of hemodynamic changes taking place in patients with liver cirrhosis and may be the hepatic response to endotoxemia in these patients . This study is a trial to assess the role bacterial infections and endotoxemia as a trigger factor for variceal hemorrhage in cirrhosis . Forty patients were studied stratified into non-bleeders and bleeders group. 13 patients of the bleeder group received antibiotics and other healthy individuals with matched age and sex were taken as a control group.