الفهرس 
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Abstract
Lichen palnus is a chronic mucocutanous inflammatory Disease of unknown etiology, however many investigations supported the role of cytokines, T lymphocytes and macrophages in the immunopathogenisis of the disease,
Many agents such as corticosteroids, retinoids, cyclosporine, dapsone, azathioprien and others have been used in managing OLP. Inspite of their numerous side effect, corticosteroids remain the bakebone in such modalities due to their immunosppressive and anti-inflammatory effects that tend to suppress the immunological reaction characteristic for lichen planus.
Cortisol is the major glucocrticoid secreted by the adrenal cortex. The presence of Cortisol in saliva has been recognized for more than 45 years. Salivary cortisol concentration follows circadian rhythm as that for serum cortisol with the maximum concentration is in the morning at 8 am. Nowadays, salivary cortisol measurement is used in monitoring HPA axis function.
Thus the aim of the study was to determine the level of cortisol in saliva as well as in the serum and their relation to the remission process in OLP patients under corticosteroid therapy.