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Abstract This study was undertaken to analyze LA volumes ,function and in patients with chronic rheumatic mitral valve regurgitation. Forty five patients with mitral regurge were compared to ten healthy control group . Unlike other techniques , echocardiography can be used to assess non-invasively LA size as well as the reservoir , conduit , and booster pump function of this chamber .We determined left atrial ( LA ) volume changes using 2D echocardiography. Left atrial cyclic volume change was calculated as the difference between maximum and minimum left atrial volumes .Left atrial volumes were measured at mitral valve opening (maximal ) and closure ( minimal ) and at onset of atrial systole ( P wave of the electrocardiogram ).The atrial active emptying was also assessed using Doppler tissue imaging , which is a simple easy method to study left atrial contractile function .Doppler –determined mitral and pulmonary venous flow was also examined .Out results indicated that two –dimensional echocardiographic measurement of LA volume can be valuable in assessing the LA function ,providing more reliable and accurate information in addition to Doppler tissue imaging than Doppler examination of mitral and pulmonary venous flow in patients with chronic mitral regurge . The results of the present study indicate that chronic rheumatic mitral valve regurge is associated with an increased in left atrial volumes , a decrease in left atrial filling , active and passive emptying function in comparison to age matched normal individuals . |