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Abstract This work was undertaken to demonstrate the effect of lead on human chromosomes m persons occupationally exposed to lead. Also to study the effect of lead nitrate alone and lead nitrate conjugated with chlorophyllin on bone marrow chromosomes in mice. IN VITRO STUDY:- Human lymphocyte cultures were used for cytogenetics Blood Samples were obtained from 2 groups of persons. Group I (Group of lead exposed workers): Twenty workers occupationally exposed to lead were considered for study. The age of workers ranged from 1 to 20 years. This group was further subdivided into 4 subgroups. Subgroup 1: Included 5 workers occupationally exposed to lead for periods ranged from 1-5 years. Subgroup 2: Included 5 wwkers occupationally exposed to lead for periods ranged from 6-10 years. Subgroup 3: Included 5 workers occupationally exposed to lead for periods ranged from 11-15 years. Subgroup 4: Included 5 workers occupationally exposed to lead for periods ranged from 16-20 years. |