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Abstract costeroids remain the key stone of treatment of nephrosis afford a practical means of classifying the disease according sensitivity, dependence or resistance to therapy. None of the diabetic patients had associated,cardiac, ionary,renal,or hepatic disease The criteria of inclusion of diabetic patients are vuria,no non—diabetic renal disease,no cardiac,respir,nor hepatic failure,no peripheral vascular disease n-diabetic nature one of the diabetics included have associated endoc athi es Before investigation all drugs known to influence ydrate and lipid metabolism are withdrawn o all the subjects included oral glucose tolerance erum and urinary creatinine,creatinine clearance,2h c-peptide,niicroalbuminuria,serum and urinary Betapglobulin ( B2—MG ),2h urinary se ( NAG ) were determined ndus examination for evidence of diabetic retinal had been done for all the patients under invest- ;1] Ten nondiabetic subjects and thirty insulin-dependentI ) diabetic patients aged between 10 and 30 years chosen for the present work. |