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Abstract
α-β-Unsaturated ketones (chalcones or benzalacetophenones) represent active intermediates for the preparation of several heterocyclic ring system. Condensation of acetophenone (54) with the appropriate aromatic aldehydes 55a-f in presence of 10% aqueous sodium hydroxide solution or piperidine afforded the corresponding α-β-unsaturated ketones 56a-f in 80-88% yields