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Abstract Toxic interaction refers to the qualitative and / or quantitative modification of the toxicity of one chemical by another. The process principally occur within the organism after the exposure phase. Interactions can either lead to a significant increase or decrease in the overall toxicity of the mixture compared to the summation of the toxicity of the components. The interactive toxicity resulting from combined exposure to chemicals is a consequence of the alteration of the toxicokinetics and / or toxicodynamics of one chemical by another. |