الفهرس 
ToxicityOnly 14 pages are availabe for public view
 |  | from | 124 |  |  |
| | | from | 124 | | |
Abstract
This work was carried out to investigate the ability of oral clonidine premedication to control ocular, cardiovascular and sympathoadrenal responses to laryngoscopy and endotracheal intubation. It includes twenty patients who were free from any cardiovascular, respiratory, metabolic or neuromuscular diseases. We excluded patients with intraocular pressure greater than 30 mmHg, patients with hypersensitivity to drugs used in this study and pregnant females. The ages of these patients were ranged from 20-55 years and the body weights were ranged from 55-75 Kg. The twenty patients were randomly allocated into two equal groups :- Group I (Control group) : received placebo tablets 90-120 minutes before induction of anaesthesia. - Group I1 (Clonidine group) : received oral clonidine 90-120 minutes before induction of anaesthesia in a dose of approximately 5 fg/Kg body weight.