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العنوان
Tumor-infiltrating foxp3+ regulatory T cells and cyclooxygenase-2 expression in mycosis fungoides /
الناشر
Nadia Reshaid Abdalaziz Alreshaid ,
المؤلف
Nadia Reshaid Abdalaziz Alreshaid
هيئة الاعداد
باحث / Nadia Reshaid Abd Al-Aziz Al-Reshaid
مشرف / Mostafa AbouElEla
مشرف / Laila Ahmed Rashed
مشرف / Rehab Aly Abdelsalam Hegazy
تاريخ النشر
2012
عدد الصفحات
106 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - Dermatology, Andrology
الفهرس
Only 14 pages are availabe for public view

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from 122

Abstract

The role of regulatory T cells (Tregs) in mycosis fungoides (MF) yielded discordant findings. Moreover, aberrant cyclooxygenase-2 (COX-2) expression has been implicated in tumorigenesis and it was shown that COX-2 is ectopically expressed in malignant T-cell lines from patients with MF. To clarify the role of both tregs as identified by FOXP-3 and COX-2 expression in the immunopathogenesis of MF and to study the relation between both entities in order to implement new strategies in the management of MF