الفهرس | Only 14 pages are availabe for public view |
Abstract Nitrate pollution involves various negative consequences for human health and ecosystems conservation, as well as domestic and wild animals. Some recent studies have underlined the reproductive toxicity of high nitrate intake in drinking water. On the other hand, several beneficial effects of some natural plants have been experimentally documented in this context. Therefore, this study was designed to investigate the ameliorating effect of administrating tumeric plant and its active component, curcumin on reproductive toxicity developed in male rats via intaking NaNO3 in drinking water at dose (550 mg/L) for four monthes. The results of the present study indicated that drinking nitrate polluted water caused various alterations in comparison with the control group as decreased absolute and relative testis and epididymas weights and reduced sperm count, male sex hormones but elevated nitric oxide level in testis. In contrast, intake of tumeric and curcumin (in particular) controlled reproductive toxicity in nitrate exposed rats. |