Search In this Thesis
   Search In this Thesis  
العنوان
Febrile neutropenia in pediatric hematology and oncology /
المؤلف
Dandash, Heba Nashaat Ibrahim Mohamed.
هيئة الاعداد
باحث / هبه نشأت إبراهيم محمد دندش
مشرف / يوسف عبدالحليم الطنباري
مشرف / علاء محمد عبدالقادر
باحث / هبه نشأت إبراهيم محمد دندش
الموضوع
Febrile neutropenia.
تاريخ النشر
2011.
عدد الصفحات
110 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية الطب - طب الأطفال
الفهرس
Only 14 pages are availabe for public view

from 135

from 135

Abstract

Febrile neutropenia is a common presentation in the practice of oncology and hematology. Neutrophils are the predominant white blood cells involved in phagocytic killing of bacteria and certain fungi (Ravandi & Hoffman, 2005). Fever in a neutropenic child must be considered a medical emergency and treated without delay. Any child known to be at risk of developing febrile neutropenia must have open access to the nearest pediatric ward (Huges et al., 2002). Neutropenia can develop in one or more conditions including decreased bone marrow production and increased destruction of neutrophils in the peripheral blood. Decreased production in the bone marrow is seen in aplastic anemias, some hereditary disorders, cancer ,or with chemotherapy (Horwitz et al., 1999).While increased destruction of neutrophils is seen in autoimmune disorders and with the use of certain medications (Zeidler & Welte, 2002). Patient of febrile neutropenia are classified into low, intermediate and high-Risk Patients (Mustafa et al., 2001; Donowitz et al., 2001; Alexander et al., 2002; Mendes et al., 2007). In this work FN was present in nearly 30% of our newly diagnosed oncology patients in agreement with the reported data, the most common sites of infection in our patients were oropharynx and lung (Rolston & Bodey, 2006).