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Abstract Thus, it can be concluded from this study that, administration of dibutylamine and sodium nitrite, precursor of nitrosamine, are potent carcinogen. Schistosomal infesta-tion on mice treated with DBA + NO2 had enhanced the hepatic injury but showed no additive effect in the case of the bladder.The present studies indicate a protective effect of SB from the carcinogenecity of nitrosamine namely dibutylintrosamine, with no effect on the liver injury induced by bilharzial infestation. |