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العنوان
A Physico Chemical and Biopharmaceutical Study on Some Hydrotropic Systems/
المؤلف
Darwesh , Enaas Abd Al Monem.
هيئة الاعداد
باحث / ايناس عبد المنعم درويش
مشرف / عبدالعزيز محمد صلاح
مشرف / غالى محمد غالى
مناقش / لبيبة كمال
الموضوع
Solid dosage forms.
تاريخ النشر
.1988
عدد الصفحات
P225. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1988
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - pharmaceutics
الفهرس
Only 14 pages are availabe for public view

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from 235

Abstract

AIM OF THE WORK: Since the first article, of Neuberg, on hydrotropy in Igl6i the research in this area has been mainly concerned with:
1. physico-chemical studies of hydrotropic salt solutions and hydrotropic systems to formulate an acceptable theory for the explanation, of the phenomenon of hydrotropy.
2. The use of hydrotropic salts in various pharmaceutical and industrial applications. The pharmaceutical applications include solubilization of water insoluble drugs, stabilization of unstable drugs, specially light sensitive ones and enhancing the absorp-tion of drugs. On the other hand, the use of hydrotropes in paper manufacture represents the most important industrial application. The literature survey indicated that most of the work has been concerned with the physicochemical proper¬ties of hydrotropes, the mechanism of hydrotropy as well as the use of hydrotropes as solubilizing agents.