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العنوان
New approaches for tetrachlorosilan mediated transformation in the synthesis of some organic compounds /
المؤلف
Khatab, Tamer Kamal Amine.
هيئة الاعداد
باحث / تامر كمال أمين خطاب
مشرف / عزت عبدالمقصود قنديل
مشرف / وحيد محمد بسيوني
مشرف / دريه صالح بدوي
مشرف / إبراهيم عبدالجليل عبدالسلام
الموضوع
Tetrachlorosilane. β-acylaminoketone. oxazines. Binary reagent. Sterichindrance. Antibacterial. Antifungal.
تاريخ النشر
2008.
عدد الصفحات
243 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
01/01/2008
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

The original work of the thesis consists of four sections. The first section deals with the synthesis of β-acylaminoketones containing a thiophene ring by the use of tetrachlorosilane/zinc chloride binary mixture as an efficient reagent. The second section of the thesis deals with the use of same reagent under different condition to synthesis some new β-acylaminoketones with poly nuclear moieties. Section three of the thesis aims to the synthesis of some new 1,3-oxazine derivatives via the reaction of substituted cyclohexanone, aldehyde, and nitrile with the same binary reagent. Section four of the thesis studies the biological activity of some newly synthesized compounds and shows that antibacterial and antifungal activities. The thesis is well written, experimental are clearly described and structures of newly synthesized compounds are well proved. .