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العنوان
Clinical and neuro-imaging studies of vertebrobasilar ischemia /
المؤلف
Abdel-Salam, Usama Ahmed Mohamed.
هيئة الاعداد
مشرف / أسامه أحمد محمد عبدالسلام
مشرف / شاكر عارف عبدالله
مشرف / صبرى علم الدين الموجى
مشرف / محمد جلال الخطيب
مناقش / شاكر عارف عبدالله
الموضوع
Vertebrobasilar insufficiency. Cerebral circulation disorders. Cerebral circulation-- Imaging.
تاريخ النشر
2008.
عدد الصفحات
248 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم الأمراض العصبية
الفهرس
Only 14 pages are availabe for public view

from 275

from 275

Abstract

The vertebrobasilar arterial system perfuses the medulla, cerebellum, pons, midbrain, thalamus, and occipital cortex. Occlusion of large vessels in this system usually leads to major disability or death; however, many lesions arise from small vessel disease and are correspondingly small and discrete. The clinical correlates of these smaller lesions consist of a variety of focal neurological deficits, depending on their location within the brainstem and hind brain. Patients with small lesions usually have a benign prognosis with reasonable functional recovery, while those with large vertebrobasilar arterial lesions carrying bad prognosis and marked disabilities. Also, neuroradiological evaluation of this part of the brain represent a major debate for neurologist as routine neuroradiological methods can missed the diagnosis of such a case. The sensitivity of MR DWI in early detection of posteriorly sited infarction in patients with posterior circulation stroke was much more than that of MRI and CT brain. MR DWI is the most sensitive test available to detect acute infarcts. Most patients with posterior-circulation strokes and some patients with TIAs related to the posterior-circulation territory show acute lesions on diffusion-weighted imaging. Our study revealed that the TCD was more conclusive than other methods in pathology detection in different patient’s groups including mild cases and TIAs group patients. We concluded from our study that; Any patients with no abnormalities detected in their MR DWI; couldn’t be diagnosed neither by CT scan nor by MRI of the brain. While MR DWI could detect abnormal pathological findings in patients with normal CT scan or MRI brain. Combined use of MR DWI & TCD is the most sensitive non invasive test which could be used to investigate acute case of vertebrobasilar ischemic stroke.