الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 118 |  |  |
| | | from | 118 | | |
Abstract
Background/Aim: Diabetic retinopathy is the most common microvascular complication of diabetes. This work aimed to evaluate erythrocyte SOD, GPx levels and serum vit E in diabetic patients with or without retinopathy. Subjects: The study was conducted on 15 diabetic patients without retinopathy and 34 patients with clinical evidence of retinopathy either proliferative or non proliferative. They were subjected to investigations in form of fasting blood glucose, lipid profile, serum creatinine, erythrocyte superoxide dismutase, glutathione peroxidase levels and serum vit E level. Results: There were significant increase in fasting blood glucose, cholesterol, triglycerides, LDL and significant decrease in HDL values in diabetic group without retinopathy or diabetic group with retinopathy. Conclusion: Free radical formation along with antioxidant deficiency in diabetes mellitus increases over time and may play an important role in the development of diabetic retinopathy. SOD, GPx, and vit E are important components of cell defence against oxidative stress. Their levels were significantly decreased in diabetics and more so in diabetic retinopathy.