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العنوان
Mri of the pancreas /
المؤلف
Ali, Sherif Abd El-Fattah Mostafa.
هيئة الاعداد
باحث / شريف عبد الفتاح مصطفي علي
مشرف / محمود عبد الشهيد راشد
مشرف / نبيل علي جاد الحق
مشرف / مها محمد زكي بلال
الموضوع
MRI. Pancreas.
تاريخ النشر
2007.
عدد الصفحات
240 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study comprised 70 patients, 40 female and 30 males with clinical suggestion of pancreatic disease . They were categorized as follows : 61 pancreatic lesions , 6 peripancreatic lesions and 3 normal cases . 42 pancreatic masses were malignant tumors , 35 were solid and 7 were cystic . 19 pancreatic lesions were benign 4 diffuse acute pancreatitis and 15 mass ( 9 were cystic and 6 were solid ) . The diagnosis in 42 malignant masses were 31 ductal adenocarcinoma , 4 lymphoma ,4mucinouscystadenocarcinoma, 1 serous cystadenocarcinoma and 2 cystic papillary and solid tumor. The diagnosis in benign pancreatic masses were 6 pancreatic pseudocysts , 4 chronic pancreatitis , 2 microcystic serous cystadenoma , 1 mucinous cystadenoma , 1 Insulinoma and 1 hemangioma . All cases were examined by conventional MRI and DWI. Dynamic MRI examination was carried out in 60 cases . Magnetic resonance imaging with new advances avoid the obstacles during MRI examination as motion and respiratory artifacts and offers high intrinsic soft tissue contrast and detailed anatomic information in most of cases and therefore has helped to characterize pancreatic diseases . True FISP is a T2 weighted rapid sequence for localization of the pancreas which display low signal ( isointense to liver ) . It is sensitive for assessment of blood vessels that appear hyperintense . True FISB and HAST T2WI are sensitive for structures containing stationary fluid as CBD , MPD , collection , cysts , necrotic tissue and cystic metastases. In and out phase sequence with breath holding give images with good anatomical details . The pancreatic lesions are hypointense in relation to the hyperintense pancreatic parenchyma . MRCP using thick-Slab, Single-Shot TSE T2- weighted Sequence in any plane with a single short breath hold and Multisection Single-Shot Thin- Slab HAST T2-weighted Sequence provides an excellent selective display of the whole extrahepatic biliary tract and pancreatic duct with no respiratory artifacts and a relatively good resolution. The ADCs of malignant solid lesions and walls and soft tissue components of malignant cystic lesion are low . The mean ADC values of benign lesions and walls and fluid content of cystic benign are more higher .We recommend its routine use in association with other advanced conventional sequence. Advantage of 3D GRE MR images include thinner sections , the ability to reformat 3D images with near isotropic resolution and diminish motion-induced phase artifacts. Gadolinium enhanced 3D GRE images shows excellent definition of the pancreatic margins and are effective in identifying small intrapancreatic tumors , peripancreatic extension of the tumor and vascular invasion MR imaging studies should be considered in the following settings: (1) early detection of pancreatic diseases for proper treatment (2) in patients with elevated serum creatinine, allergy to iodine contrast, or other contraindications for iodine contrast administration; (3) in patients with prior CT imaging who have focal enlargement of the pancreas with no definable mass; (4) in patients in whom clinical history is worrisome for malignancy and in whom findings on CT imaging are equivocal or difficult to interpret; and (5) in situations requiring distinction between chronic pancreatitis with focal enlargement and pancreatic cancer. Patients with biochemical evidence of islet-cell tumors should be examined by MR imaging as the first-line