Search In this Thesis
   Search In this Thesis  
العنوان
Physical parameters affecting the optical coherence tomography (OCT) for diagnosis of retinal and optic disc disorders /
المؤلف
Mokpel, Nessreen Khairy Mohamed.
هيئة الاعداد
باحث / vNessreen Khairy Mohamed Mokpel
مشرف / Mostafa Kamal
مناقش / Hamed Ibrahim Mohamed Farag
مناقش / Raof Amin El-Nafis
الموضوع
Retina Diseases. Retina Physiopathology. Retinal Diseases Diagnosis.
تاريخ النشر
2007.
عدد الصفحات
108 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الفيزياء وعلم الفلك
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of Physics
الفهرس
Only 14 pages are availabe for public view

from 123

from 123

Abstract

The present study included 40 patients (74 eyes) and 44 volunteers (80 eyes); they were divided into two groups as following: First group: includes patients with clinically evidence of glaucoma (49 eyes of 25 patients), and normal eyes served as control group (52 eyes of 26 volunteers), and they had OCT testing on the optic nerve head using 1.73 nerve head scan protocol. Second group: includes patients with clinically evidence diabetic retinopathy (25 eyes of 15 patients), and control group (28 eyes of 18 volunteers), and they had OCT testing on the macular region using radial lines scan protocol. Patients were not considered for this study if they had high myopia, previous ocular surgery, or anterior segment opacity. All patients and volunteers underwent through the following: 1.Medical history. 2.Complete ophthalmological examination. 3.Humphrey 24-2 visual field testing in case of the first group. 4.Flourescein angiography in case of the second group. 5.Optical Coherence Tomography. Optical Coherence Tomography is useful in measuring changes in retinal thickness, which accompanies many retinal diseases, in cases of diabetic macular edema OCT showed increase in the macular thickness which correlated with areas of dye leakage in the fluorescein angiography, and in cases of glaucoma OCT showed thinning of nerve fiber layer thickness. OCT system achieved extremely high sensitivity to the weak optical reflections from the retina; image acquisition time was recorded as 1 second, the best signal-to-noise ratio was accomplished, S/N ratio was approximately the same in glaucoma and DME groups about 52 dB, and it was higher in the two control groups about 55 dB.