الفهرس | Only 14 pages are availabe for public view |
Abstract lhis thesis is devoted to the analysis of some pharma- ceutically-important nitro compounds in bulk, and in dosage forms. Part 1 presents a literature review revealing the methods of analysis described for the studied compounds. Part 11 IS concerned with the determination of some nitro compounds, adopting the induced difference spectroscopy techn ique. This is based on the spectral changes induced by reduction, either with Zno/HCl or Zno/NH4Cl. The investigated compounds are furazolidone, metronidazole, nifuroxime, niridazole, nitrazepam, nitrofurantoin and nitro- furazone. Part III describes the simultaneous determina- tion of certain nitrofuran compounds present in admixture with other compounds using the two-components and absorbance- ratio methods. In this respect, mixtures containing nitro- furantoin and phenazopyridine as well as furazolidone and berberine were investigated. Part IV IS devoted to the calorimetric determination of certain nitro compounds thro- u~h reduction followed by diazo-coupling with ethylaceto- acetoacetate. In part V, details concerning the reagents, apparatus and procedures adopted are described. |