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العنوان
Ovarian reserve assessment and management of poor responders /
المؤلف
Taki El-Din, Ahmed Mohsen Abd EL-­Aziz.
هيئة الاعداد
باحث / احمد محسن عبدالعزيز تقي الدين
مشرف / ناصر سامح اللقاني
مشرف / كمال ابراهيم انوار
مشرف / اسامة محمود وردة
مناقش / يحيى وفا
الموضوع
Fertility Human. Ovarian reserve. Gynecology. Obstetrics.
تاريخ النشر
2005.
عدد الصفحات
128 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية الطب - التوليد وامراض النساء
الفهرس
Only 14 pages are availabe for public view

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Abstract

The terminology of ?ovarian reserve?, simply means the ovarian capacity to cohort sufficient and good oocytes to lead a concept cycle, is relatively new. It posed itself in our expressions especially in assisted reproductive technology (ART) era. This elegant terminology differs from the traditional one ?ovulating status?, so that a woman may ovulate; yet having a poor ovarian reserve and vice versa, how<U+2019>s puzzling? Now assessing ovarian reserve become more or less crurial for assessing women<U+2019>s fertility potential especially when deciding ART or other fertility promoting procedures e.g. laparoscopy. Conclusions: In the clinicians<U+2019> practice, the assessment of ovarian reserve should provide both the physician and patient with a realistic expectation of the chances for pregnancy, and also identify those patients who are destined for failure. Age as an ovarian reserve test was found to be of prognostic value in the general infertile population, but not in women entering an ART programme. Neither chronological age, nor most of the other tests are able to estimate the chance of achieving a pregnancy, and consequently their results should be interpreted with caution; they should never be used to exclude patients from care, as long as their clinical relevance is uncertain. Most of these tests are performed within an ART population. Poor responders represent a challenging group of infertility patients who fail to respond to controlled ovarian hyperstimulation during the course of assisted reproduction treatment. Although, poor response has been investigated since the eighties, many aspects of this condition are still controversial and no consensus has been reached on the management of these patients. The existing data cannot be easily compared due to the heterogeneity of the research design and methodology and the number of prospective randomized trials of sufficient sample size is limited. In addition, more research in the identification and understanding of underlying factors is needed together with a better understanding of the pathophysiological basis, of ovarian aging and of the progressive reduction in ovarian reserve.