الفهرس 
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Abstract
This study was conducted to investigate the toxic effects of aflatoxin B1 (AFB1) on mono-sex Nile tilapia Oreochromis niloticus fingerlings and attempting to detoxify these drastic effects by using some nutritious agents. Therefore, half percent of each of these nutritious agents namely Bio-Buds-2x, chamomile flowers, aspirin and ginger were added to aflatoxic (100 ppb aflatoxin B1) diet for fingerlings. These diets were offered 6 days a week at 3% daily of actual biomass in glass aquaria in duplicate/treatment in an indoor feeding experiment lasted 14 weeks. The aflatoxic diet led to the worst fish growth performance and survival rate, feed and protein utilization, internal organs indices, carcass composition and residues of AFB1 (ppb) in the whole body of fish and the tested parameters of blood haematology and biochemistry of the experimented fish. As well as, protein analysis showed that there were remarkable variations in the number of bands and their intensity among all treatments. Also, esterase activities affected by the exposure to the toxin and toxin plus Bio-Buds-2x, chamomile flowers, aspirin and ginger. Yet, AFB1 in the fish diets led to severe histological alterations in all tested organs (livers, kidneys, intestines and gills, except in the gonads of treated fish). However, dietary ginger inclusion alleviated aflatoxicosis symptoms by fish, since it improved all the above tested parameters of aflatoixcated fish. Generally, the obtained results in the present study indicated that the ginger was the best detoxifying agent of aflatoxin, followed by aspirin and chamomile flowers respectively