الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
 |  | from | 51 |  |  |
| | | from | 51 | | |
Abstract
This study was carried out in Clinical Pathology Departement and Mansoura
University Children Hospital(MUCH) .Pediatric patients were referred from
outpatient clinic and from other departments of MUCH to Haematology Departement
of the same hospital .They were complaining of bleeding manifestations like
prolonged bleeding after injuries, following tooth extraction, circumcision and
following trauma. Also patients presented with epistaxis, gum bleeding, ecchymoses
and haemartherosis.
A total of 105 pediatrtc patients were referred to MUCH. They were divided into
2 groups ;
1. Pediatric patients with congenital coagulation disorders. They were 75 patients
(45 cases with haemophilia A ,15 cases with haemophilia B , 5 cases with
VWD, 2 cases with factor X deficiency,2 cases with factor V deficiency, 2 cases
with factor X1deficiency and 4 cases with factor XIII deficiency). Their mean
age was 45.36±48.59 months.
2. Pediatric patients with acquired coagulation disorders .They were 30 patient (15
cases with liver disease , 10 cases with haemorrhagic disease of the neoborn and
5 cases with DIC). Their mean age was 56.13±61.61 months.
- Haemophilias are the most prevalent congenital coagulation disorders among
children attending MUCH.
- Factor VIII C / VWF Ag ratio is a useful marker for detection of carriers in
haemophilia families.
- Inhibitors to VIII and IX do exist in a significant fraction in haemophilic
patients treated with factor concentrate.
- Liver disease is the most common aquired coagulation disorders among
children attending MUCH.