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العنوان
Propacetamol versus tramadol infusion during anesthesia for children undergoing strabismus surgery :
المؤلف
Hassan, Hossam El­-Din Ahmed Mostafa.
هيئة الاعداد
باحث / حسام الدين احمد مصطفى حسن
مشرف / مصطفى محمد على سعيد
مشرف / عاطف دميان دميان
مشرف / امجد عبدالمجيد زغلول
الموضوع
Strabismus. Postoperative - Nausea and vomiting. Propacetamol. Tramadol.
تاريخ النشر
2005.
عدد الصفحات
83 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة المنصورة - كلية الطب - التخدير والعناية المركزة الجراحية
الفهرس
Only 14 pages are availabe for public view

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Abstract

This study was designed to compare the analgesic potency of intraoperative IV infusion of either propacetamol 30 mg/ kg, or tramadol 2 mg/kg in pediatric patients aging 3­7 years undergoing strabismus correction. The patients involved in this study (n=45) were randomly assigned by sealed envelop method into 3 equal groups according to the analgesic drug used. Patients of the 1st group had received only 100 ml 0.9% saline IV infusion. Patients of the 2nd group had received propacetamol 30 mg/kg diluted in 100 ml 0.9% saline while, patients of the 3rd group had received tramadol 2 mg/kg diluted in 100ml 0.9(R@?(Bo saline. In this study, we found that, intraoperative IV infusion of propacetamol 30 mg/ kg or tramadol 2 mg/kg offered a good postoperative analgesia for children undergoing strabismus surgery and the analgesic potency of propacetamol was nearly equivalent to that of tramadol and the duration of action of both drugs was nearly equal (6 hours). Both groups showed significant differences as compared with the control group which showed the most severe postoperative pain score and more postoperative analgesic consumption, especially in the first 6 postoperative hours. Although statistically insignificant, there was a reduction in the incidence of PONV from 40% in control group to 33.3% in tramadol group to 26.7% in propacetamol group, suggesting the contribution of pain in the production of PONV. As regard the intraoperative haemodynamics, both HR and MAP showed a significant increase 1 min after induction of anesthesia in the three studied groups but returned again to nearly the basal values 5 min after induction and continued till the end of operation. There were no significant differences in both HR and MAP values among the three groups. The total incidence of oculocardiac reflex in all studied patients was 22%. The difference of incidence of OCR between the three groups was statistically insignificant.