الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Objective: To evaluate the different modalities of diagnosis and treatment of cases with accidental intraarterial drug injection (IADI). Patients and methods: This study included (28), who are divided into (2) major groups as, retrospective (13 patients) (10 male and 3 female) (from Nov2002 to Jul2004) and prospective (15 patients) (11 male and 4 Female) (from Aug2004 to Jan2006). All patients get radiological investigations in the form of assessment by pocket Doppler, color duplex and Photoplethysmography (PPG) but all prospective patients get also digital subtraction angiography, CTangiography and post contrast MRangiography. All retrospective patients get treatment as following: systemic use of prostaglandin E1, I2, LMWH, dexamethazone and antiplatelets as Acetylesalysilic acid (Aspirin). Results: It was found that (6 patients) (46.16%) get digits amputation, (4 patients) (30.77%) get wrist or above wrist amputation and (3 patients) (23.07%) get normal outcome. Of the (8 patients) with a TIS 2, (5 patients) of the (6 patients) within 48 hours of IADI and (1 patients) of the (2 patients) treated more than 48 hours after injection had a normal outcome. This difference was not statistically significant. In contrast, for patients with severe injury (TIS > 2) initiation of treatment within 48 hours of injection was effective in preventing tissue necrosis and neurologic dysfunction. Of (7 patients) with a TIS > 2, the patient that treated less than 48 hours after injection get an abnormal outcome and only (1 patient) (6.67%) of the (6 patients) (40%) that treated more than 48 hours after injection get normal outcome and the othet (5 patients) (33.34%) get abnormal outcome. Conclusions: In our study, it was found that the treatment of the cases with Accidental intraarterial drug injections (IADI) with intraarterial cannulation and injection of (Hparin and thrombolytic therapy) get better outcome than treatment of these cases with only systemic heparinization which is obvious in limb saving in the prospective group.