الفهرس 
Congenital heart diseasesOnly 14 pages are availabe for public view
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Abstract
This prospective randomized study was designed to compare pulmonary and systemic hemodynamics as well as the effects on myocardial contractility of two anesthetic regimens; propofol-ketamine total intravenous anesthesia TIVA and sevoflurane volatile induction maintenance anesthesia VIMA in pediatric patients suffering from congenital heart disease with left-to-right shunt. Forty pediatric patients of either sex aged 1-12 years were included in this study. Patients were randomly allocated into two equal groups regarding the anesthetic technique. Patients in the first group (GS) received VIMA with sevoflurane, while patients in the second group (GPK) received TIVA with propofol-ketamine. The present study showed that hemodynamic parameters were comparable in both groups except that FS and EF and SVRI were significantly higher in GPK. There were no significant differences after ketamine-propofol TIVA in comparison with the basal values as regard HR, MAP, QpI, QsI, Qp/Qs ratio, PVRI, SVRI, and PVR/SVR ratio; however, there were significant increases in FS and EF. There were no significant differences after sevoflurane VIMA in comparison with the basal values as regard HR, FS, EF, Qp, Qs, Qp/Qs ratio, PVR/SVR ratio, however, there were significant decreases in MAP, PVRI, and SVRI. Administration of 100% oxygen for 15 min was associated with significant decrease in PVRI and PVR/SVR ratio and significant increase in Qp and Qp/Qs ratio. Recovery times were shorter in GS but discharge time was similar in both groups