الفهرس 
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Abstract
LPR is defined as reflux of the gastric contents through the upper esophageal sphincter into the laryngopharynx resulting in-group of symptoms and findings. Diagnosis of LPRD is based on a combination of factors, including symptoms, laryngeal findings, and diagnostic test results. The most common symptom of LPRD is hoarseness/dysphonia, chronic throat clearing, chronic cough, globus pharyngeus, postnasal drip and dysphagia. Reflux-related conditions include reflux laryngitis, granulomas, paroxysmal laryngospasm, polypoid degeneration, laryngeal stenosis, carcinoma of the larynx, and functional voice disorders. The clinical manifestation of LPRD can be divided into three groups, based upon severity, minor, major and life threatening. Dual-channel pH-metry is considered to be the gold standard diagnostic tool for LPRD. Despite this, there are several problems associated with pH probe testing. Antireflux therapy: The traditional treatment of GERD includes dietary and lifestyle modifications and the use of antacids, an H2 receptor antagonist, and/or a once-daily proton-pump inhibitor (PPI) is not effective in LPRD. The treatment of LPRD usually must be more aggressive and prolonged than the treatment of GERD. An initial 6-month period of medical therapy should be attempted .In LPR, acid must be suppressed around the clock.