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العنوان
Prediction of malignancy in the supra hyoid neck :
الناشر
Eman Abd Elsalam Amer,
المؤلف
Amer, Eman Abd Elsalam.
هيئة الاعداد
باحث / إيمان عبدالسلام زكي عامر
مشرف / محمود عبدالشهيد راشد
مشرف / محمد العقدة
مشرف / سامية منير زكي
مشرف / ماهر محمود عرفة
الموضوع
Head-- Tumors.
تاريخ النشر
2004.
عدد الصفحات
128 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم الاشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Conventional MRI imaging was widely used for evaluation of head and neck tumor, yet it is not capable of providing relevant clues to the malignancy. Recently DWI and ADC mapping has a further aid in accurate diagnosis of malignant tumor, and provide a reliable and adequate information for differentiation benign from malignant tumors. This study aimed to evaluate the role of MRI and DWI in distinguishing benign from malignant lesions at the suprahyoid neck lesions in 55 patients were 34 male and 21 female. All patient was subjected to full clinical examination and MRI examination. MRI examination included spin echo and DWI sequences with b0, b500 and b1000, ADC values were calculated by placing multiple ROI, inside each lesion. According to the MRI appearance and final diagnosis, 4 groups were included: -Group I: Solid benign lesions (n= 23). -Group II : Solid malignant lesions (n= 25). -Group III: Cystic benign lesion (n= 5). -Group IV: Cystic malignant lesions (n= 4). - The mean ADC of solid malignant lesions (94 x 10-5 mm2/s 30 x 10-5 mm2/s) was significantly lower than the mean ADC of solid benign lesions (146 x 10-5 mm2/s 41) with P = 0.0001. - ADC value of 137 x 10-5mm2/s or less was used for prediction of malignancy with 26 out 29 malignant lesions were correctly diagnosed as its ADC values were less than 137 x 10-5 mm2/s. Whereas 25 out of 28 benign lesions were truly diagnosed using ADC values higher than 137x10-5mm2/s. On the other hand there were 3 cases incorrectly diagnosed as benign lesion (false -ve). Also 3 cases falsely diagnosed as malignant lesions (false +ve). Thus the statistical data of the examination diagnosis of malignancy were as follows: - Sensitivity = 82% (27/33) - Specificity= 86% (24/28) - Accuracy = 84% (51/61) - +ve predictive value= 87% (27/31) - -ve predictive value = 80% (24/30)